Research articles on Immunostimulators:
HIV-1 infection and AIDS.
A boost for the immune system.

Isoprinosine have both immunomodulating and antiviral properties. It helps to treat acute and chronic viral infections. Isoprinosine acts on the immune system to restore impaired cell-mediated response to baseline in addition to enhancing humoral response. It has also a direct antiviral activity. Isoprinosine can reduce the intensity of symptoms and shorten the duration of the viral infection. In addition, the occurrence of complications is reduced and the frequency and severity of recurrences is minimised. Isoprinosine is an immunoenhancing agent in aged humans.

You can find an extensive list of recent scientific research abstracts about ISOPRINOSINE here

  RHODIOLA ROSEA (dry roots)  

Preparation of tea: cut fine 5g of Rhodiola Rosea roots. 1 cup of boiling water pour in roots and leave for (brew) at least 4 hours. Than filter. Daily dosage: 1/5 cup - 3-5 times per day. For better taste dilute Rhodiola Rosea tea with juice, tonic or other herbal tea.

Preparation of tincture for personal usage: Mill 30 g of Rhodiola Rose roots in a coffee-grinder no less than 5-10 mm, add 150 ml of light spirits (30-40%), agitate and steep 3-5 days at room temperature. Separate and filter the extract. Dosage: ? tsp. x 3 times per day.

You can find an extensive list of recent scientific research abstracts about RHODIOLA ROSEA here

  RHODIOLA ROSEA (dry extract tablets, total rosavins 40%)  

A large proportion of all aging diseases (perhaps 70-80%) is believed to occur because the stress level is too high, and/or too long-term. High-stress modern living is probably the main factor causing chronic disease and premature aging. Fortunately, Mother Nature has an answer to this challenge - a unique class of herbal products called "adaptogens".
Adaptogens have the broadest spectrum of healing properties of any herbal medicine, but their unique value is that they specifically relieve stress.

The main effects of adaptogens are an increased availability of energy during the day, a reduction of stressed feelings, increased endurance, greater mental alertness, and deep and restful sleep. Also, adaptogens significantly accelerate the recovery process after illness. The author of this article was ill for many years, and became weaker and weaker, despite trying a variety of medicines and supplements. Doctors could not diagnose the illness, but probably it was an autoimmune disorder, with too many symptoms to name. One day one of my friends had sent me roots of Rhodiola Rosea from Moscow (Russia) and advised me to prepare Rhodiola water tea to drink. After some trial and error, I found this Siberian root worked better than anything else I had tried; and it increased the effectiveness of other supplements as well. I decided to search to find out more about this wonderful herbal adaptogen.

According to modern science, adaptogens are natural plant products that increase the body's ability to cope with internal and external stress factors, and normalize the functions of the organism. They help maintain the stable internal environment inside the organism known as homeostasis. An important characteristic is that they are safe, possessing few known side effects.

You can find an extensive list of recent scientific research abstracts about RHODIOLA ROSEA here


Neurol Clin. 2002 Nov;20(4):983-1011
HIV-1 infection and AIDS.
Belman AL.
University of Alabama at Birmingham, School of Medicine, Department of Medicine, Birmingham, USA.

Since the initial descriptions of AIDS in the late 1970s, much has been learned about the biology of HIV-1 and the cells it infects. Much has also been learned about mother-to-infant viral transmission and the natural history of HIV-1 infection. Key studies led to strategies for interrupting mother-to-infant transmission, resulting in a significant decline in neonatal HIV-1 infection. More proficient diagnostic techniques made early diagnosis of HIV-1-infected neonates and infants possible during asymptomatic or mildly symptomatic disease stages. Major advances in treatment led to the control of viral replication and thereby altered the course of disease progression. HIV-1/AIDS-associated neurologic disorders declined in parallel. In countries where these therapies are readily available, a dramatic decline in the number of infants born HIV-1 infected has been realized as has a markedly improved survival rate of those infected. Many questions remain, however. The long-term effects of prenatal exposure to antiretroviral agents are not yet known and continue to be studied. Just exactly how HAART therapy may affect early signs of pediatric HIV-1/AIDS-associated CNS disease, should they develop, is unclear. As new anti-retroviral agents are developed and new combination drug regimens are instituted, the potential for neurologic complications, toxicities, and adverse drug interactions (e.g., with antiepileptic drugs (AEDS)) exists and needs to be identified and monitored.


AIDS Anal Afr. 1997 Jan;7(4):1
A boost for the immune system.
Knight VC.

PIP: A 15-member medical research team at Tygerberg Hospital in Cape Town, South Africa, has developed a compound which halted, and even reversed, the progression of HIV disease in human clinical trial subjects. The compound is a mixture of sterols and sterolins, which are found in all plants, yet identified through the more than $10 million of medical research and clinical trial funding provided by Essential Sterolin Products, a small, family-owned South African pharmaceutical company which has recently acquired a world patent for the compound. The compound does not affect viral replication, but instead helps the patient's natural immune system fight off HIV. 300 volunteers with HIV were involved in the double-blind placebo clinical trials launched in 1993. The compound's therapeutic power became clear after 6 months, so the trial was ended on ethical grounds. Administration of the compound has halted patients' physical deterioration, T-cell counts have increased by several hundred percent in some patients, HIV loads are decreasing, there have been no apparent side effects, and patients report both weight gain and a reduction in skin irritations. The compound is taken in pill form three times per day before meals at the current cost of approximately 40 US cents per day. The head of Essential Sterolin Products wants to keep the compound's price low so that people with HIV can afford it. The company is currently negotiating with two international drug corporations to market the compound worldwide as therapy for HIV patients. The capsules are already on the market in South Africa as a food supplement in health nutrition stores.

on the Adriatic Coast
The Anti-Aging Fasting Program consists of a 7-28 days program (including 3 - 14 fasting days). 7-28-day low-calorie diet program is also available .
More information
    The anti-aging story (summary)
Introduction. Statistical review. Your personal aging curve
  Aging and Anti-aging. Why do we age?
    2.1  Aging forces (forces that cause aging
Internal (free radicals, glycosylation, chelation etc.) 
External (Unhealthy diet, lifestyle, wrong habits, environmental pollution, stress, poverty-change "poverty zones", or take it easy. etc.) 
    2.2 Anti-aging forces
Internal (apoptosis, boosting your immune system, DNA repair, longevity genes) 
External (wellness, changing your environment; achieving comfortable social atmosphere in your life, regular intake of anti-aging drugs, use of replacement organs, high-tech medicine, exercise)
    2.3 Aging versus anti-aging: how to tip the balance in your favour!
    3.1 Caloric restriction and fasting extend lifespan and decrease all-cause mortality (Evidence)
      Human studies
Monkey studies
Mouse and rat studies
Other animal studies
    3.2 Fasting and caloric restriction prevent and cure diseases (Evidence)
Hypertension and Stroke
Skin disorders
Mental disorders
Neurogical disorders
Asthmatic bronchitis, Bronchial asthma
Bones (osteoporosis) and fasting
Arteriosclerosis and Heart Disease
Cancer and caloric restriction
Cancer and fasting - a matter of controversy
Eye diseases
Chronic fatigue syndrome
Sleeping disorders
Rheumatoid arthritis
Gastrointestinal diseases
    3.3 Fasting and caloric restriction produce various
      biological effects. Effects on:
        Energy metabolism
Lipids metabolism
Protein metabolism and protein quality
Neuroendocrine and hormonal system
Immune system
Physiological functions
Reproductive function
Cognitive and behavioral functions
Biomarkers of aging
    3.4 Mechanisms: how does calorie restriction retard aging and boost health?
        Diminishing of aging forces
  Lowering of the rate of gene damage
  Reduction of free-radical production
  Reduction of metabolic rate (i.e. rate of aging)
  Lowering of body temperature
  Lowering of protein glycation
Increase of anti-aging forces
  Enhancement of gene reparation
  Enhancement of free radical neutralisation
  Enhancement of protein turnover (protein regeneration)
  Enhancement of immune response
  Activation of mono-oxygenase systems
  Enhance elimination of damaged cells
  Optimisation of neuroendocrine functions
    3.5 Practical implementation: your anti-aging dieting
        Fasting period.
Re-feeding period.
Safety of fasting and low-calorie dieting. Precautions.
      3.6 What can help you make the transition to the low-calorie life style?
        Social, psychological and religious support - crucial factors for a successful transition.
Drugs to ease the transition to caloric restriction and to overcome food cravings (use of adaptogenic herbs)
Food composition
Finding the right physician
    3.7Fasting centers and fasting programs.
  Food to eat. Dishes and menus.
    What to eat on non-fasting days. Dishes and menus. Healthy nutrition. Relation between foodstuffs and diseases. Functional foods. Glycemic index. Diet plan: practical summary. "Dr. Atkins", "Hollywood" and other fad diets versus medical science

Bread, cereals, pasta, fiber
Glycemic index
Meat and poultry
Sugar and sweet
Fats and oils
Dairy and eggs
Nuts and seeds
Food composition

  Anti-aging drugs and supplements
    5.1 Drugs that are highly recommended
      (for inclusion in your supplementation anti-aging program)
        Vitamin E
Vitamin C
Co-enzyme Q10
Lipoic acid
Folic acid
Flavonoids, carotenes
Vitamin B
Vinpocetine (Cavinton)
Deprenyl (Eldepryl)
    5.2 Drugs with controversial or unproven anti-aging effect, or awaiting other evaluation (side-effects)
        Phyto-medicines, Herbs
      5.3 Drugs for treatment and prevention of specific diseases of aging. High-tech modern pharmacology.
        Alzheimer's disease and Dementia
Immune decline
Infections, bacterial
Infections, fungal
Memory loss
Muscle weakness
Parkinson's disease
Prostate hyperplasia
Sexual disorders
Stroke risk
Weight gaining
    5.4 The place of anti-aging drugs in the whole
      program - a realistic evaluation
    6.1 Early diagnosis of disease - key factor to successful treatment.
      Alzheimer's disease and Dementia
Cataracts and Glaucoma
Genetic disorders
Heart attacks
Immune decline
Infectious diseases
Memory loss
Muscle weakness
Parkinson's disease
Prostate hyperplasia
Stroke risk
Weight gaining
    6.2 Biomarkers of aging and specific diseases
    6.3 Stem cell therapy and therapeutic cloning
    6.4 Gene manipulation
    6.5 Prosthetic body-parts, artificial organs
Bones, limbs, joints etc.
Heart & heart devices
    6.6 Obesity reduction by ultrasonic treatment
  Physical activity and aging. Experimental and clinical data.
        Aerobic exercises
Weight-lifting - body-building
Professional sport: negative aspects
  Conclusion: the whole anti-aging program
    9.1 Modifying your personal aging curve
      Average life span increment. Expert evaluation.
Periodic fasting and caloric restriction can add 40 - 50 years to your lifespan
Regular intake of anti-aging drugs can add 20-30 years to your lifespan
Good nutrition (well balanced, healthy food, individually tailord diet) can add 15-25 years to your lifespan
High-tech bio-medicine service can add 15-25 years to your lifespan
Quality of life (prosperity, relaxation, regular vocations) can add 15-25 years to your lifespan
Regular exercise and moderate physical activity can add 10-20 years to your lifespan
These approaches taken together can add 60-80 years to your lifespan, if you start young (say at age 20). But even if you only start later (say at 45-50), you can still gain 30-40 years

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    9.2 The whole anti-aging life style - brief summary 
    References eXTReMe Tracker
        The whole anti-aging program: overview

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